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Boosting glutathione may prevent or limits these issues [35]

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If outcomes differ between runs, a clear record of lot identifiers and preparation assumptions helps isolate whether differences are related to model variables, assay variables, or procurement variables

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The likelihood ratio based on the objective function value was used to test different hypotheses regarding the structure of the variancecovariance matrix for inter-individual variability and residual variability models, and to assess the covariate effects on toxicokinetic parameters